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A Medical Mystery — Painless Ulcers

Stephen Morris-Jones, M.R.C.P., and Martin Weber, M.D.

N Engl J Med 2004; 350:1442April 1, 2004

Article

A 23-year-old Peace Corps volunteer lived in a traditional mud hut with a thatched roof in a rural savannah village in Gambia. Several painless ulcers developed on his lower legs during a three-month period. The lesions did not respond to local antimicrobial therapy (2 percent fucidic acid ointment applied four times daily for one week) or systemic antimicrobial therapy (500 mg of floxacillin four times a day for two weeks). A typical lesion was a clean ulcer with a raised, purplish, indurated edge. The diameter was similar to that of a Gambian dalasi, which is 3.1 cm. The patient had not previously traveled outside the United States. What is the diagnosis?

Stephen Morris-Jones, M.R.C.P.
Martin Weber, M.D.
Medical Research Council Laboratories, Fajara, Gambia

Citing Articles (1)

Citing Articles

  1. 1

    Morris-Jones, Stephen, Weber, Martin, . (2004) Medical Mystery: Painless Ulcers — The Answer. New England Journal of Medicine 350:22, 2313-2314
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