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Severe Constipation

Gustavo Cumbo-Nacheli, M.D.

N Engl J Med 2008; 358:e26May 29, 2008

Article

A 46-year-old man with a history of cerebral palsy presented with difficulty in breathing, which had gradually increased during the previous 2 weeks. He was admitted to the intensive care unit with a diagnosis of sepsis, for which he received intravenous fluids, antibiotics, and mechanical ventilation. Computed tomography of the abdomen showed a severely distended colon with fecal stasis compressing the abdominal organs and elevating the diaphragm. There were no signs of colonic perforation. After initial conservative measures were unsuccessful in evacuating the impaction, multiple enemas with the use of sodium phosphate and soapsuds finally dislodged the blockage after 2 weeks. The patient's recovery was unremarkable.

Gustavo Cumbo-Nacheli, M.D.
Wayne State University School of Medicine, Detroit, MI 48201