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Lipomatosis of the Tongue

Hiroshi Murakami, M.D., and Naoki Tamasawa, M.D.

N Engl J Med 2009; 360:e33June 25, 2009

Article

An 88-year-old man presented with diffuse, painless swelling of the lateral borders of his tongue (Panel A). The swelling had been slowly increasing during the previous 20 years. Yellowish tumors with a smooth, shiny surface were visible. There was no frank macroglossia, dysphagia, dysarthria, or sleep apnea. No other tumors were identified anywhere in the body, including the oral cavity and the gastrointestinal tract, which were evaluated endoscopically. There was no cervical lymphadenopathy. Serum glucose and lipid levels were normal. The patient had no atherosclerotic disease, he did not drink alcohol, and no family members were similarly affected. Examination of a specimen from an incisional biopsy showed lobules of mature adipose tissue that were consistent with lipomatosis (Panel B, arrows); there was no evidence of liposarcoma. He received no treatment. Lipomas are very common; however, isolated lipomatosis of the tongue is rare.

Hiroshi Murakami, M.D.
Naoki Tamasawa, M.D.
Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan

Citing Articles (1)

Citing Articles

  1. 1

    Byung Eon Hwang, Eun Jung Lee, Ho Sung Park, Ki Hwan Hong. (2011) A Case of Symmetrical Lipomatosis of the Tongue. Korean Journal of Otorhinolaryngology-Head and Neck Surgery 54:10, 719
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