Images in Clinical Medicine

A Medical Mystery — Arthritis

Tim L. Jansen, M.D., Ph.D., and Anneke Spoorenberg, M.D., Ph.D.

N Engl J Med 2006; 354:2375June 1, 2006

• Slide

Article

A 51-year-old woman with a 15-year history of rheumatoid arthritis presented with swelling and loss of function of the right shoulder. Magnetic resonance imaging of the shoulder revealed severe destruction of the humeral head with an elevated signal of the bone marrow (Panel A). Puncture revealed 60 ml of a white colloidal fluid (Panel B). The results of polarizing microscopy are shown in Panel C. What is the diagnosis?

Tim L. Jansen, M.D., Ph.D.
Anneke Spoorenberg, M.D., Ph.D.
Medisch Centrum Leeuwarden, 8934 AD Leeuwarden, the Netherlands

Citing Articles (2)

Citing Articles

1. 1

   Alexander P. Rozin, Kohava Toledano, Doron Markovits, Alexandra Balbir-Gurman. (2010) Imaging mystery. Rheumatology International 30:10, 1409-1410
   CrossRef

2. 2

   Jansen, Tim L., Spoorenberg, Anneke, . (2006) Medical Mystery: Arthritis — The Answer. New England Journal of Medicine 355:4, 421-422
   Full Text

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