Book Review

Malignant Mesothelioma: Advances in Pathogenesis, Diagnosis, and Translational Therapies

N Engl J Med 2006; 354:1437-1438March 30, 2006

Article

Malignant Mesothelioma: Advances in Pathogenesis, Diagnosis, and Translational Therapies
Edited by Harvey I. Pass, Nicholas J. Vogelzang, and Michele Carbone. 854 pp., illustrated. New York, Springer-Verlag, 2005. $139. ISBN: 0-387-22949-3

Malignant mesothelioma is an uncommon neoplasm usually associated with exposure to asbestos. Because of its low incidence, thorough reviews of the topic are hard to find. Harvey Pass and colleagues have edited an up-to-date, comprehensive book that includes a wide range of information, from a historical perspective to descriptions of the latest treatment. The authors, who are renowned experts in the field, have written chapters on the carcinogenesis, molecular genetics, and clinical aspects of mesothelioma.

Malignant Mesothelioma is suitable for a broad audience. Laboratory researchers will use it as a resource for information about the pathogenesis, animal models, molecular genetics, and cell lines of mesothelioma. Public health investigators and oncologists will appreciate the epidemiology section, which covers the types of exposure to asbestos that are related to the development of mesothelioma, as well as other related factors such as simian virus 40 and radiation. Clinicians will benefit from this complete guide to the presentation, prognosis, imaging, and treatment of the disease. I highly recommend this book to all who are interested in mesothelioma.

Julie R. Brahmer, M.D.
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231