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Correction

Hypertrophic Obstructive Cardiomyopathy

N Engl J Med 2004; 351:1038September 2, 2004

Article

Hypertrophic Obstructive Cardiomyopathy (Clinical Practice, N Engl J Med 2004:350;1320 - 1327) . As a clarification to the information provided on page 1323 in Table 2 regarding the recommended doses of beta-blockers, the authors have submitted the following statement: “For metoprolol, atenolol, and propranolol, reasonable starting doses are 25 mg twice daily, 50 mg once daily, and 40 mg twice daily, respectively. The maximum recommended total daily doses of these agents in patients with angina pectoris are 400 mg, 100 mg, and 320 mg, respectively. However, in our own practice, we have found that larger doses of beta-blockers are frequently necessary to control symptoms in patients with hypertrophic cardiomyopathy, and in this setting we have used total daily doses of up to 600 mg of metoprolol or 600 mg of propranolol. Equivalent doses of atenolol (up to 300 mg) could also be used.”

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