Correspondence

Tissue Matching before the Era of HLA Typing

N Engl J Med 2004; 350:624February 5, 2004

Article

To the Editor:

In the summer of 1961, I “volunteered” for $50 to receive skin grafts in order to help determine the most suitable bone marrow donor for a teenage girl who was severely anemic as a result of treatment with chloramphenicol. I noted that the mother's graft was rejected in a manner similar to that of the patient's, whereas the brother's graft lasted several more days before rejection occurred and closely retained its larger size and shape (Figure 1Figure 1Early Tissue Typing and Donor Selection — The “Third Man” Technique.). I was told that the girl did not live to receive a transplant. I have carried the scars as a medical curiosity for 40 years.

David A. Willard, M.D.
Medical Center at Princeton, Princeton, NJ 08540

Citing Articles (1)

Citing Articles

1. 1

   van Rood, Jon J., . (2004) Weighing Optimal Graft Survival through HLA Matching against the Equitable Distribution of Kidney Allografts. New England Journal of Medicine 350:6, 535-536
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