Correction

Estrogen and the Risk of Breast Cancer

N Engl J Med 2001; 344:1804June 7, 2001

Article

Estrogen and the Risk of Breast Cancer (Review Article, N Engl J Med 2001:344;276 - 285) . On page 276, the sentence that begins 11 lines from the bottom of the right-hand column should have read, “Flaxseed is a rich dietary source of both mammalian lignans and α-linolenic acid, which exert antiestrogenic effects by both binding to the estrogen receptor and inhibiting the synthesis of estrogen.³⁴” On page 278, Figure 1 and its legend contained errors. The corrected figureFigure 1Pathways of Estrogen Synthesis and Catabolism and the Sensitivity of Tissue to Estrogens. is reprinted with its legend below. On page 279, the last sentence in the right-hand column should have read, “The 2-hydroxy metabolites are converted to anticarcinogenic methoxylated metabolites (2-methoxyestrone and 2-methoxyestradiol, 2-hydroxyestrone and 2-hydroxyestradiol 3-methyl ether) by catechol O-methyltransferase.”

Citing Articles (1)

Citing Articles

1. 1

   Michael B. Sporn, Sherie A. Dowsett, John Mershon, Henry U. Bryant. (2004) Role of raloxifene in breast cancer prevention in postmenopausal women: Clinical evidence and potential mechanisms of action. Clinical Therapeutics 26:6, 830-840
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