Images in Clinical Medicine
Lung Cancer Presenting as an Ankle Metastasis
N Engl J Med 2000; 343:268July 27, 2000
- Article
Figure 1 A 45-year-old man with a 70-pack-year history of smoking began to have pain and then swelling in his right foot and ankle. He had no history of trauma. The radiographic findings were inconclusive, and the chest film was normal. Magnetic resonance imaging of the foot showed a large enhancing lesion of the calcaneus (arrow in Panel A). A bone scan (Panel B) showed abnormalities in the right calcaneus and the right humerus consistent with the presence of a metastatic tumor. A needle biopsy of the calcaneus lesion showed moderately differentiated adenocarcinoma; the results of immunohistochemical staining were consistent with the presence of a primary lung cancer. Four months later, cough and chest discomfort developed and the primary bronchogenic carcinoma became apparent. The patient was treated with multiple courses of radiotherapy and chemotherapy, with symptomatic relief, but died 21 months after diagnosis.
Ronald C. McGarry, M.D., Ph.D.
University of Nebraska Medical Center, Omaha, NE 68198-1050- Citing Articles (1)
Citing Articles
1
Masanori Daibata, Kentaro Bandobashi, Hirokuni Taguchi. (2005) Calcaneus involvement by multiple myeloma. American Journal of Hematology 80:4, 311-312
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