Images in Clinical Medicine
Keratoacanthoma
N Engl J Med 1999; 340:708March 4, 1999
- Article
Figure 1 A 71-year-old woman who had had a basal-cell carcinoma presented with a six-week history of an enlarging lesion on the upper part of her right arm (Panel A). The well-circumscribed crateriform nodule, which had a keratotic core and measured 2 by 2 cm, appeared clinically to be a benign keratoacanthoma. An excisional biopsy was performed. Histologic analysis revealed a proliferation of squamous cells that were derived from the epidermis and formed a large, keratin-filled crater lined by thickened, papillary, glycogen-rich epithelium, findings consistent with a diagnosis of keratoacanthoma (Panel B; hematoxylin and eosin, ×10). One year after the excision, the patient had no evidence of new or recurrent disease.
Hensin Tsao, M.D., Ph.D.
Massachusetts General Hospital, Boston, MA 02114Steven R. Tahan, M.D.
Beth Israel Deaconess Medical Center, Boston, MA 02215- Citing Articles (2)
