Images in Clinical Medicine
Cutaneous Cryptococcosis
N Engl J Med 1997; 336:998April 3, 1997
- Article
Figure 1 A 32-year-old man infected with the human immunodeficiency virus presented with multiple papules of various sizes, many of which were umbilicated. The lesions were located mainly on his face (Panel A), with lesser involvement of the trunk, buttocks, arms, and legs. A Tzanck preparation of the gelatinous core obtained by curettage from one of the papules revealed encapsulated yeast forms (Panel B; Wright's stain, ×400). This simple technique permitted a rapid presumptive diagnosis of Cryptococcus neoformans. Subsequent cultures of cerebrospinal fluid, blood, and skin grew C. neoformans. After the patient received a total dose of 1500 mg of amphotericin B intravenously, the lesions gradually resolved, and he was subsequently treated with daily oral fluconazole. He remained free of skin lesions during the subsequent three-month period.
Donald J. Baker, M.D.
Annette C. Reboli, M.D.
University of Medicine and Dentistry of New Jersey/Robert Wood Johnson Medical School at Camden, Camden, NJ 08103- Citing Articles (3)
Citing Articles
1
2011. Cryptococcosis. , 303-332.
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J.B. Nayak, M.N. Brahmbahtt, C.V. Savalia, M. Pal, B.B. Bhanderi. (2010) Cryptococcosis: A Garded Mycosis Threat. Research Journal of Veterinary Sciences 3:2, 101-112
CrossRef3
L. Ramos, C. Lopez, C. Gomez, S. Mathurin, A. Mateo. (2001) Case Report. Cutaneous cryptococcosis in a patient with systemic erythematous lupus. Mycoses 44:9-10, 419-421
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