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Kim Eagle, M.D., Editor

Angioedema of the Intestine

Kate W.P. Gregory, B.S., and Rufus C. Davis, M.D.

N Engl J Med 1996; 334:1641June 20, 1996

Article

Figure 1 Abdominal computed tomography was performed in a 58-year-old woman with acute abdominal pain, nausea, vomiting, and abdominal distention. The patient had had recurrent swelling of the tongue and pharynx during therapy with lisinopril, but the medication had been continued. On the scan, the mucosa of a loop of small intestine is markedly thickened, and the irregularities within the wall are most consistent with the presence of edema (thick arrow). The valvulae conniventes are prominent and widened (thin arrow), resulting in a severely narrowed lumen. All of the patient's symptoms resolved within 24 hours after the discontinuation of lisinopril.

Kim Eagle, M.D.

Kate W.P. Gregory, B.S.
Rufus C. Davis, M.D.
Vanderbilt University, Nashville, TN 37232

Citing Articles (13)

Citing Articles

  1. 1

    Stephen C. Wei, Karen Fitzgerald, Dean D. T. Maglinte. (2007) CT findings in small bowel angioedema: a cause of acute abdominal pain. Emergency Radiology 13:5, 281-283
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  2. 2

    Joel Handler. (2005) Quality of Life and Antihypertensive Drug Therapy. The Journal of Clinical Hypertension 7:5, 274-285
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  3. 3

    Domenic A. Sica. (2004) Angiotensin-Converting Enzyme Inhibitors Side Effects?Physiologic and Non-Physiologic Considerations. The Journal of Clinical Hypertension 6:7, 410-416
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  4. 4

    Johan Persson, Peter Morsing, Per-Olof Gr??nde. (2004) Vasopeptidase inhibition with omapatrilat increases fluid and protein microvascular permeability in cat skeletal muscle. Journal of Hypertension 22:3, 637-644
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  5. 5

    Domenic A. Sica, Henry R. Black. (2002) Angioedema in Heart Failure: Occurrence With ACE Inhibitors and Safety of Angiotensin Receptor Blocker Therapy. Congestive Heart Failure 8:6, 334-345
    CrossRef

  6. 6

    Reza Abdi, Victor M. Dong, Cynthia J. Lee, K. Adu Ntoso. (2002) Angiotensin II Receptor Blocker–Associated Angioedema: On the Heels of ACE Inhibitor Angioedema. Pharmacotherapy 22:9, 1173-1175
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  7. 7

    Troy D. Schmidt, Kevin M. McGrath. (2002) Angiotensin-Converting Enzyme Inhibitor Angioedema of the Intestine:. The American Journal of the Medical Sciences 324:2, 106-108
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  8. 8

    Henriette Farkas, George Harmat, P??l N. Kaposi, Istv??n Kar??di, B??la Fekete, George F??st, K??lm??n F??y, Anik?? Vass, Lilian Varga. (2001) Ultrasonography in the diagnosis and monitoring of ascites in acute abdominal attacks of hereditary angioneurotic oedema. European Journal of Gastroenterology & Hepatology 13:10, 1225-1230
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  9. 9

    Michael P. Chase, Gale S. Fiarman, Francis J. Scholz, Richard P. MacDermott. (2000) Angioedema of the Small Bowel Due to an Angiotensin-converting Enzyme Inhibitor. Journal of Clinical Gastroenterology 31:3, 254-257
    CrossRef

  10. 10

    Richard Haydon. (2000) Urticaria-angioedema and nonurticarial angioedema. Current Opinion in Otolaryngology & Head and Neck Surgery 8:3, 239-244
    CrossRef

  11. 11

    Soccorsa Sofia, Anna Casali, Luigi Bolondi. (1999) Sonographic findings in abdominal hereditary angioedema. Journal of Clinical Ultrasound 27:9, 537-540
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  12. 12

    D. L. JARDINE, J. C. ANDERSON, A. D. McCLINTOCK. (1999) Delayed diagnosis of recurrent visceral angiooedema secondary to ACE inhibitor therapy. Australian and New Zealand Journal of Medicine 29:3, 377-378
    CrossRef

  13. 13

    (1996) Angioedema of the Intestine. New England Journal of Medicine 335:20, 1534-1535
    Full Text

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