Images in Clinical Medicine

Kim Eagle, M.D., Editor

Bony Metastases

Mark Glazer, M.D., and Vidya V. Sagar, M.D.

N Engl J Med 1995; 332:370February 9, 1995

• Slide

Article

Figure 1 The results of whole-body bone scintigraphy in a 58-year-old man who reported backache are shown. Plain bone films were unremarkable. Scintigraphy revealed numerous foci of increased uptake of tracer (“hot spots”), a finding consistent with metastatic disease. Focally increased uptake reflects increased osteoblastic activity associated with the attempted repair of diseased bone. Subsequent studies revealed the tumor to be prostate cancer.

Kim Eagle, M.D.

Mark Glazer, M.D.
University of Chicago, Chicago, IL 60637

Vidya V. Sagar, M.D.
Medical Center of Delaware, Newark, DE 19718