Owl's-Eye Cells

Richard Herriot, M.R.C.P., M.R.C.Path., and Elizabeth S. Gray, F.R.C.Path.

N Engl J Med 1994; 331:649September 8, 1994

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Figure 1 Owl's-Eye Cells.

The photomicrograph shows a section of kidney taken at autopsy from a three-month-old boy who died of disseminated cytomegalovirus infection contracted in utero. A single periglomerular renal tubule contains large, intranuclear viral inclusion bodies typical of those found in cells infected with cytomegalovirus. Such inclusion bodies are commonly seen at autopsy or in biopsy specimens from the kidneys, lungs, and other organs in cases of congenital or acquired cytomegalovirus infection. (Hematoxylin and eosin, x1920.).

Kim Eagle, M.D.

Richard Herriot, M.R.C.P., M.R.C.Path.
Elizabeth S. Gray, F.R.C.Path.
Aberdeen Royal Infirmary, Aberdeen AB9 2ZD, United Kingdom

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