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Showing 1 to 20 of 85 NEJM Weekly CME Exams, Past 6 Months

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  • Original Article

    Melphalan–prednisone (MP) has long been the treatment of choice for patients with multiple myeloma who are older than 65 years of age. The introduction of new agents in the past few years has substantially changed the treatment of multiple myeloma. MP plus either thalidomide or bortezomib is…

    • May 10, 2012
    • Palumbo, Antonio, Hajek, Roman, Delforge, Michel, Kropff, Martin, Petrucci, Maria Teresa, Catalano, John, Gisslinger, Heinz, Wiktor-Jędrzejczak, Wiesław, Zodelava, Mamia, Weisel, Katja, Cascavilla, Nicola, Iosava, Genadi, Cavo, Michele, Kloczko, Janusz, Bladé, Joan, Beksac, Meral, Spicka, Ivan, Plesner, Torben, Radke, Joergen, Langer, Christian, Yehuda, Dina Ben, Corso, Alessandro, Herbein, Lindsay, Yu, Zhinuan, Mei, Jay, Jacques, Christian, Dimopoulos, Meletios A.,
    • N Engl J Med 2012; 366:1759-1769
  • Case Records of the Massachusetts General Hospital

    Presentation of Case. Dr. Sarah Gee (Dermatology): A 43-year-old woman was admitted to the hospital because of fever and a generalized rash. The patient had a history of atopic dermatitis and had been in her usual health until approximately 1 week before admission, when a painful, pruritic rash…

    • May 10, 2012
    • Cabot, Richard C.Harris, Nancy Lee, Shepard, Jo-Anne O., Rosenberg, Eric S., Cort, Alice M., Ebeling, Sally H.Peters, Christine C., Mackool, Bonnie T., Goverman, Jeremy, Nazarian, Rosalynn M.,
    • N Engl J Med 2012; 366:1825-1834
  • Review Article

    Certification to perform catheter-based interventions for coronary artery disease was originally limited to hospitals that had the capability to perform cardiac surgery on site. However, there has been a progressive worldwide trend to allow percutaneous coronary intervention (PCI) to be performed…

    • May 10, 2012
    • Shahian, David M., Meyer, Gregg S., Yeh, Robert W., Fifer, Michael A., Torchiana, David F.,
    • N Engl J Med 2012; 366:1814-1823
  • Original Article

    Radioiodine (131I) is administered to patients with thyroid cancer after total thyroidectomy for three reasons–: first, to eradicate normal-thyroid remnants (ablation) in order to achieve an undetectable serum thyroglobulin level; second, to irradiate any neoplastic focus in order to decrease the…

    • May 3, 2012
    • Schlumberger, Martin, Catargi, Bogdan, Borget, Isabelle, Deandreis, Désirée, Zerdoud, Slimane, Bridji, Boumédiène, Bardet, Stéphane, Leenhardt, Laurence, Bastie, Delphine, Schvartz, Claire, Vera, Pierre, Morel, Olivier, Benisvy, Danielle, Bournaud, Claire, Bonichon, Françoise, Dejax, Catherine, Toubert, Marie-Elisabeth, Leboulleux, Sophie, Ricard, Marcel, Benhamou, Ellen,
    • N Engl J Med 2012; 366:1663-1673
  • Original Article

    Aortic stenosis is associated with high mortality after the appearance of cardiac symptoms. Nevertheless, many patients do not undergo surgical aortic-valve replacement owing to real or perceived increased risks associated with surgery.– Transcatheter aortic-valve replacement (TAVR) has emerged…

    • May 3, 2012
    • Kodali, Susheel K., Williams, Mathew R., Smith, Craig R., Svensson, Lars G., Webb, John G., Makkar, Raj R., Fontana, Gregory P., Dewey, Todd M., Thourani, Vinod H., Pichard, Augusto D., Fischbein, Michael, Szeto, Wilson Y., Lim, Scott, Greason, Kevin L., Teirstein, Paul S., Malaisrie, S. Chris, Douglas, Pamela S., Hahn, Rebecca T., Whisenant, Brian, Zajarias, Alan, Wang, Duolao, Akin, Jodi J., Anderson, William N., Leon, Martin B.,
    • N Engl J Med 2012; 366:1686-1695
  • Clinical Problem-Solving

    Foreword. In this Journal feature, information about a real patient is presented in stages (boldface type) to an expert clinician, who responds to the information, sharing his or her reasoning with the reader (regular type). The authors' commentary follows. Stage. A 38-year-old woman living in…

    • May 3, 2012
    • Solomon, Daniel A., Fanta, Christopher H., Levy, Bruce D., Loscalzo, Joseph,
    • N Engl J Med 2012; 366:1725-1730
  • Original Article

    Owing to the many advantages that computed tomography (CT) has over other diagnostic tests, including ultrasonography,– CT has assumed a paramount position in the evaluation of adults with suspected appendicitis. Despite historical debate, the increased use of CT has been consistently found to…

    • April 26, 2012
    • Kim, Kyuseok, Kim, Young Hoon, Kim, So Yeon, Kim, Suyoung, Lee, Yoon Jin, Kim, Kwang Pyo, Lee, Hye Seung, Ahn, Soyeon, Kim, Taeyun, Hwang, Seung-sik, Song, Ki Jun, Kang, Sung-Bum, Kim, Duck-Woo, Park, Seong Ho, Lee, Kyoung Ho,
    • N Engl J Med 2012; 366:1596-1605
  • Original Article

    The growing incidence of obesity and type 2 diabetes mellitus globally is widely recognized as one of the most challenging contemporary threats to public health. Uncontrolled diabetes leads to macrovascular and microvascular complications, including myocardial infarction, stroke, blindness,…

    • April 26, 2012
    • Schauer, Philip R., Kashyap, Sangeeta R., Wolski, Kathy, Brethauer, Stacy A., Kirwan, John P., Pothier, Claire E., Thomas, Susan, Abood, Beth, Nissen, Steven E., Bhatt, Deepak L.,
    • N Engl J Med 2012; 366:1567-1576
  • Case Records of the Massachusetts General Hospital

    Presentation of Case. Dr. Norifumi Kamo (Medicine): A 62-year-old man was admitted to this hospital because of paresthesias, weight loss, jaundice, and anemia. The patient had been well until approximately 2 months before admission, when numbness, tingling ("pins and needles"), and burning in his…

    • April 26, 2012
    • Cabot, Richard C.Harris, Nancy Lee, Shepard, Jo-Anne O., Rosenberg, Eric S., Cort, Alice M., Ebeling, Sally H.Peters, Christine C., Puig, Alberto, Mino-Kenudson, Mari, Dighe, Anand S.,
    • N Engl J Med 2012; 366:1626-1633
  • Review Article

    The impact of certain skin diseases on the lives of those affected tends to be underestimated or even dismissed as simply a "cosmetic problem." Alopecia areata exemplifies such a condition, owing to its substantial disease burden and its often devastating effects on the patient's quality of life…

    • April 19, 2012
    • Gilhar, Amos, Etzioni, Amos, Paus, Ralf,
    • N Engl J Med 2012; 366:1515-1525
  • Case Records of the Massachusetts General Hospital

    Presentation of Case. Dr. Helen H. Yeung (Pediatrics): A 10-month-old girl was seen in the emergency department at this hospital because of vomiting and episodes of unresponsiveness. The patient had been well until 2 a.m. on the day of admission, when she awoke with vomiting that was associated…

    • April 19, 2012
    • Cabot, Richard C.Harris, Nancy Lee, Shepard, Jo-Anne O., Rosenberg, Eric S., Cort, Alice M., Ebeling, Sally H.Peters, Christine C., Sassower, Kenneth C., Allister, Lauren M., Westra, Sjirk J.,
    • N Engl J Med 2012; 366:1527-1536
  • Original Article

    The strategies of percutaneous coronary intervention (PCI) and coronary-artery bypass grafting (CABG) for revascularization have been compared in randomized clinical trials. Although the best way to control for treatment-selection bias is to conduct a randomized trial, such trials often have…

    • April 19, 2012
    • Weintraub, William S., Grau-Sepulveda, Maria V., Weiss, Jocelyn M., O'Brien, Sean M., Peterson, Eric D., Kolm, Paul, Zhang, Zugui, Klein, Lloyd W., Shaw, Richard E., McKay, Charles, Ritzenthaler, Laura L., Popma, Jeffrey J., Messenger, John C., Shahian, David M., Grover, Frederick L., Mayer, John E., Shewan, Cynthia M., Garratt, Kirk N., Moussa, Issam D., Dangas, George D., Edwards, Fred H.,
    • N Engl J Med 2012; 366:1467-1476
  • Review Article

    Dengue is a self-limited, systemic viral infection transmitted between humans by mosquitoes. The rapidly expanding global footprint of dengue is a public health challenge with an economic burden that is currently unmet by licensed vaccines, specific therapeutic agents, or efficient vector-control…

    • April 12, 2012
    • Simmons, Cameron P., Farrar, Jeremy J., van Vinh Chau, Nguyen, Wills, Bridget,
    • N Engl J Med 2012; 366:1423-1432
  • Original Article

    Patients who present to the emergency department with signs and symptoms consistent with a possible acute coronary syndrome pose a diagnostic dilemma.– Despite the introduction of clinical decision rules– and the improved sensitivity of cardiac markers,– most patients are admitted to the…

    • April 12, 2012
    • Litt, Harold I., Gatsonis, Constantine, Snyder, Brad, Singh, Harjit, Miller, Chadwick D., Entrikin, Daniel W., Leaming, James M., Gavin, Laurence J., Pacella, Charissa B., Hollander, Judd E.,
    • N Engl J Med 2012; 366:1393-1403
  • Case Records of the Massachusetts General Hospital

    Presentation of Case. Dr. Pritha Sen (Medicine): A 60-year-old man with a history of schizophrenia was admitted to this hospital in late spring because of weakness, rash, and renal failure. The patient was in his usual state of health until several days before admission, when fatigue and myalgias…

    • April 12, 2012
    • Cabot, Richard C.Harris, Nancy Lee, Shepard, Jo-Anne O., Rosenberg, Eric S., Cort, Alice M., Ebeling, Sally H.Peters, Christine C., Channick, Richard N., Lorenzo, Mayra E., Wu, Carol C., Hoang, Mai P.,
    • N Engl J Med 2012; 366:1434-1443
  • Clinical Practice

    Foreword. This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations. Stage. A 39-year-old…

    • April 5, 2012
    • Ismail-Beigi, Faramarz,
    • N Engl J Med 2012; 366:1319-1327
  • Original Article

    Artemisinin-based combination therapy is critical for the effective treatment and control of Plasmodium falciparum malaria.– However, reports from the Cambodian–Thai border indicate the emergence of artemisinin tolerance or resistance in P. falciparum.– Pyronaridine–artesunate is a fixed…

    • April 5, 2012
    • Rueangweerayut, Ronnatrai, Phyo, Aung Pyae, Uthaisin, Chirapong, Poravuth, Yi, Binh, Tran Quang, Tinto, Halidou, Pénali, Louis K., Valecha, Neena, Tien, Nong Thi, Abdulla, Salim, Borghini-Fuhrer, Isabelle, Duparc, Stephan, Shin, Chang-Sik, Fleckenstein, Lawrence,
    • N Engl J Med 2012; 366:1298-1309
  • Clinical Problem-Solving

    Foreword. In this Journal feature, information about a real patient is presented in stages (boldface type) to an expert clinician, who responds to the information, sharing his or her reasoning with the reader (regular type). The authors' commentary follows. Stage. A 56-year-old woman with symptoms…

    • April 5, 2012
    • Safdar, Nasia, Abad, Cybele L., Kaul, Daniel R., Saint, Sanjay,
    • N Engl J Med 2012; 366:1336-1340
  • Clinical Therapeutics

    Foreword. This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are…

    • March 29, 2012
    • Diamond, David A., Mattoo, Tej K.,
    • N Engl J Med 2012; 366:1218-1226
  • Review Article

    Until recently, the treatment for diabetic retinopathy relied almost exclusively on managing the metabolic dysregulation of diabetes mellitus until the severity of vascular lesions warranted laser surgery. Intensive metabolic control remains a highly effective means of controlling retinopathy and…

    • March 29, 2012
    • Antonetti, David A., Klein, Ronald, Gardner, Thomas W.,
    • N Engl J Med 2012; 366:1227-1239

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The NEJM Review CME Program is a comprehensive home study program based on the most clinically relevant New England Journal of Medicine articles.

These 50-credit exams consist of board-style questions written to emphasize key issues from the most recent six-month volume of NEJM issues. The exams are offered in March and September. Learn more about the NEJM Review CME Program.

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