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Correspondence
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Volume 359:657-659 August 7, 2008 Number 6
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Treatment Outcomes in Extensively Resistant Tuberculosis

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To the Editor: Extensively drug-resistant tuberculosis, which is defined as tuberculosis that is resistant to rifampin, isoniazid, a fluoroquinolone, and a second-line injectable agent, poses a major challenge for global health.1,2,3,4 There are few published data from studies comparing treatment outcomes for patients with extensively drug-resistant tuberculosis with the outcomes for patients with multidrug-resistant tuberculosis, which is defined as tuberculosis that is resistant to at least isoniazid and rifampin.

Among a series of 205 consecutive patients who were referred to our specialty medical center for respiratory diseases and treated between 1984 and 1998 for multidrug-resistant tuberculosis, the overall long-term success . . . [Full Text of this Article]



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