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Original Article
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Volume 359:152-157 July 10, 2008 Number 2
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Familial Myeloma
Henry T. Lynch, M.D., Kelly Ferrara, M.S., Bart Barlogie, M.D., Ph.D., Elizabeth A. Coleman, Ph.D., Jane F. Lynch, B.S.N., Dennis Weisenburger, M.D., Warren Sanger, Ph.D., Patrice Watson, Ph.D., Henry Nipper, Ph.D., Vinetta Witt, Ph.D., and Stephan Thomé, M.D.

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SUMMARY

We describe a family with five cases of multiple myeloma, three cases of monoclonal gammopathy of undetermined significance (MGUS), and five cases of prostate cancer in two generations. The putative progenitor had progeny with two female partners. The progeny had prostate cancer, multiple myeloma, and MGUS.


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From Creighton University School of Medicine (H.T.L., K.F., J.F.L., P.W., S.T.); Nebraska Medical Center (D.W., W.S.); and Creighton University Medical Center (H.N.) — all in Omaha; the University of Arkansas for Medical Sciences, Little Rock (B.B., E.A.C.); and Newberry College, Newberry, SC (V.W.).

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