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Previous Volume 359:1590-1601 October 9, 2008 Number 15 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presented. The article ends with the author's clinical recommendations.

A 45-year-old woman undergoes core needle biopsy of a breast mass 4 cm in diameter and fine-needle aspiration of a palpable axillary lymph node, the results of both of which are found to be consistent with invasive ductal carcinoma . . . [Full Text of this Article]

The Clinical Problem

Pathophysiology and Effect of Therapy

Clinical Evidence

Clinical Use

Reconstruction with Implants

Autogenous Tissue–Based Reconstruction

Immediate versus Delayed Reconstruction

Costs

Advantages and Disadvantages

Implants

Autogenous Tissue–Based Reconstruction

Areas of Uncertainty

Guidelines

Recommendations

Source Information

From the Department of Surgery, Memorial Sloan-Kettering Cancer Center; and the Weill Medical College of Cornell University — both in New York.

Address reprint requests to Dr. Cordeiro at the Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Ave., Rm. MRI1007B, New York, NY 10021.

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