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Previous Volume 359:1477-1485 October 2, 2008 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.

Shortly after being elbowed in the flank during a pickup basketball game, a 35-year-old healthy man has severe, colicky abdominal pain followed by gross hematuria. He is hospitalized, and a renal ultrasound scan reveals bilateral polycystic kidneys and liver cysts, previously unknown to the patient. The blood pressure is 160/100 mm Hg. The serum creatinine concentration is 0.9 mg per deciliter (80 . . . [Full Text of this Article]

The Clinical Problem

Strategies and Evidence

Diagnosis

Monitoring for Disease Progression

Genetic Testing

Screening for Brain Aneurysm

Treatment

            Hypertension and Left Ventricular Hypertrophy

            Hematuria

            Urinary Tract Infection

            Renal Stones

            Renal Pain

            Renal Insufficiency

Women

Areas of Uncertainity

Screening

Prevention of Disease Progression

Water Intake

Guidelines

Conclusions and Recommendations

Source Information

From the Kidney Institute and the Department of Internal Medicine, Kansas University Medical Center, Kansas City.

An audio version of this article is available at www.nejm.org.

Address reprint requests to Dr. Grantham at the Kidney Institute and Department of Internal Medicine, Kansas University Medical Center, 3901 Rainbow Blvd., Kansas City, KS 66160, or at jgrantha@kumc.edu.

This article has been cited by other articles:

• Belibi, F. A., Edelstein, C. L. (2009). Unified Ultrasonographic Diagnostic Criteria for Polycystic Kidney Disease. J. Am. Soc. Nephrol. 20: 6-8 [Full Text]