Randomized trials have established that the prophylactic useof implantable cardioverter–defibrillators (ICDs) prolongssurvival in patients with left ventricular dysfunction thatis due to myocardial infarction1 or associated with heart failurefrom any cause.2 One of the pivotal trials, the Sudden CardiacDeath in Heart Failure Trial (SCD-HeFT) (ClinicalTrials.govnumber, NCT00000609
[ClinicalTrials.gov]
), compared ICD therapy or amiodarone withplacebo in 2521 patients with symptomatic heart failure dueto ischemic or nonischemic left ventricular dysfunction.2 Thattrial showed that among patients who had an ICD as comparedwith those who received a placebo, there was an absolute reductionin mortality of . . . [Full Text of this Article]
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From the Division of Cardiology, Hamilton Health Sciences Centre, McMaster University, Hamilton, ON, Canada.
This article has been cited by other articles:
(2008). QOL and Mortality Among Heart Failure Patients with Implantable Cardioverter-Defibrillators. JWatch General
2008: 4-4
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