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Dr. Allyson K. Bloom (Medicine): A 57-year-old woman was admitted to this hospital because of abdominal pain and weakness. One month earlier, a laparoscopic Roux-en-Y gastric bypass and cholecystectomy were performed for treatment of obesity and gallstones. Pathological examination of a liver-biopsy specimen revealed nonalcoholic fatty liver disease. The immediate postoperative course was uncomplicated, and she was discharged 2 days after surgery. At follow-up visits, she reported poor oral intake, episodes of tachycardia (which had occurred intermittently in the past), intermittent passage of watery stool and dark urine, and suprapubic and epigastric pain; on two occasions, fluids were administered intravenously
Differential Diagnosis
Abdominal Pain
Red Urine
Rapidly Progressive Weakness
Other Features of This Case
Acute Porphyria
Diagnosis of Porphyria
Classification of Porphyrias
Causes of Attacks of Acute Porphyria
Management of Attacks of Acute Porphyria
Clinical Diagnosis
Dr. Herbert L. Bonkovsky's Diagnosis
Pathological Discussion
Anatomical Diagnosis
Source Information
From the Departments of Medicine and Molecular, Microbial, and Structural Biology, University of Connecticut Health Center, Farmington; the Department of Medicine, Carolinas Medical Center, Charlotte, NC, and University of North Carolina, Chapel Hill; and the Department of Biology, University of North Carolina, Charlotte (H.L.B.); and the Departments of Neurology (P.S.), Radiology (Z.R.), and Pathology (E.T.H-W., T.J.F.), Massachusetts General Hospital; and the Departments of Neurology (P.S.), Radiology (Z.R.), and Pathology (E.T.H-W., T.J.F.), Harvard Medical School — both in Boston.
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