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Editorial
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Volume 358:2172-2174 May 15, 2008 Number 20
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Multiple Biomarker Panels for Cardiovascular Risk Assessment
James A. de Lemos, M.D., and Donald M. Lloyd-Jones, M.D., Sc.M.

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 by Zethelius, B.
-PubMed Citation
Guidelines for the assessment of cardiovascular risk remain focused squarely on established risk factors.1 Although it is known that tools based on these risk factors, such as the Framingham Risk Score, have a number of limitations when applied in clinical practice — performing reasonably well for groups but not necessarily for individuals and underestimating long-term risk among younger persons2 — it has proved surprisingly difficult to improve on established risk factors for the prediction of cardiovascular disease. Of the many strategies that have been proposed to improve risk stratification, the measurement of plasma biomarkers is particularly attractive as compared with . . . [Full Text of this Article]


Source Information

From the Donald W. Reynolds Cardiovascular Clinical Research Center, University of Texas Southwestern Medical Center, Dallas (J.A.L.); and the Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago (D.M.L.-J.).


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