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Previous Volume 358:1402-1405 March 27, 2008 Number 13 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: We respectfully challenge the notion of Iannuzzi and colleagues (Nov. 22 issue)¹ that in all cases (other than cases of Löfgren's syndrome) "a biopsy specimen should be obtained from the involved organ that is most easily accessed." We believe that not all patients with sarcoidosis require a tissue biopsy. Physicians can be confident of a diagnosis of sarcoidosis in some patients after clinical, radiographic, and epidemiologic considerations, much in the same way that idiopathic pulmonary fibrosis can be diagnosed with high specificity in patients with typical clinical and high-resolution computed tomographic (CT) findings.^2,3 Asymptomatic patients with hilar . . . [Full Text of this Article]

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