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Correspondence
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Volume 351:937-938 August 26, 2004 Number 9
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New Drugs for Rheumatoid Arthritis

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 by Olsen, N. J.
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 by O'Dell, J. R.
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To the Editor: In an examination of the data that support the use of anti–tumor necrosis factor (TNF) drugs for rheumatoid arthritis, as reviewed by O'Dell (June 17 issue)1 and by Olsen and Stein (May 20 issue),2 one critical point is that there has been just a single randomized trial of infliximab and adalimumab (in which the new agent plus methotrexate was compared with methotrexate alone) and there have been only two trials of etanercept (one very recent3 and therefore not mentioned by Olsen and Stein). In addition, the number of patients enrolled in these trials was small (the number . . . [Full Text of this Article]


Related Letters:

Rheumatoid Arthritis
Burchini G., Orsi C., Bhattacharya N., O'Dell J. R.
Extract | Full Text | PDF  
N Engl J Med 2004; 351:1360-1361, Sep 23, 2004. Correspondence

New Drugs for Rheumatoid Arthritis
Roberts L. J., Kalil A. C., Messori A., Santarlasci B., Vaiani M.
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N Engl J Med 2004; 351:2659-2661, Dec 16, 2004. Correspondence

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