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Previous Volume 347:2162-2164 December 26, 2002 Number 26 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Widespread use of nonsteroidal antiinflammatory drugs (NSAIDs) among the elderly has resulted in a large population of persons at risk for ulcer complications. Selective cyclooxygenase-2 (COX-2) inhibitors were introduced with the hope that they would not cause gastrointestinal complications. However, it is not clear that this has been the case, and now that the dust has settled somewhat, it is possible to take a dispassionate look at the problem.^1,2 In this issue of the Journal, Chan et al.³ report a randomized comparison of celecoxib and diclofenac plus omeprazole among patients in Hong Kong who had previously had bleeding from ulcers . . . [Full Text of this Article]

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Celecoxib versus Diclofenac and Omeprazole to Prevent Recurrent Ulcer Bleeding
Nurmohamed M. T., Lems W. F., Lanas A., McKeogh D. F., Chan F. K.L., Graham D. Y.
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N Engl J Med 2003; 348:2464-2466, Jun 12, 2003. Correspondence

This article has been cited by other articles:

• Jacobsen, R. B, Phillips, B. B. (2004). Reducing Clinically Significant Gastrointestinal Toxicity Associated with Nonsteroidal Antiinflammatory Drugs. The Annals of Pharmacotherapy 38: 1469-1481 [Abstract] [Full Text]  
• Mulshine, J. L., Atkinson, J. C., Greer, R. O., Papadimitrakopoulou, V. A., Van Waes, C., Rudy, S., Martin, J. W., Steinberg, S. M., Liewehr, D. J., Avis, I., Linnoila, R. I., Hewitt, S., Lippman, S. M., Frye, R., Cavanaugh, P. F. Jr. (2004). Randomized, Double-Blind, Placebo-Controlled Phase IIB Trial of the Cyclooxygenase Inhibitor Ketorolac as an Oral Rinse in Oropharyngeal Leukoplakia. Clin. Cancer Res. 10: 1565-1573 [Abstract] [Full Text]  
• Nurmohamed, M. T., Lems, W. F., Lanas, A., McKeogh, D. F., Chan, F. K.L., Graham, D. Y. (2003). Celecoxib versus Diclofenac and Omeprazole to Prevent Recurrent Ulcer Bleeding. NEJM 348: 2464-2466 [Full Text]  
• (2003). NSAID-Associated Recurrent Ulcer Bleeding: COX-2 Inhibitors vs. Acid Reduction. JWatch Gastroenterology 2003: 5-5 [Full Text]