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Correction to Liberman et al., N Engl J Med 333(22):1437-1444 November 30, 1995.

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Volume 334:733-735 March 14, 1996 Number 11
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Alendronate in Postmenopausal Osteoporosis

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by Liberman, U. A.
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by Liberman, U. A.
To the Editor: The study by Liberman et al. (Nov. 30 issue)1 on the effects of alendronate on bone mineral density and the incidence of fractures in postmenopausal women with osteoporosis is important, but in our view not as exciting as it first seems. The authors pooled the results for women and, with respect to fractures, for doses of alendronate in two multicenter studies — an approach that at first seems valid. However, as shown in Table 2 of the article, the incidence of new vertebral fractures was lower in the U.S. study than in the multinational study, both in . . . [Full Text of this Article]

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