Case 19-2008 -- A 63-Year-Old HIV-Positive Man with Cutaneous Merkel-Cell Carcinoma

doi:10.1056/NEJMcpc0803063

Volume 358:2717-2723		June 19, 2008		Number 25

Case 19-2008 — A 63-Year-Old HIV-Positive Man with Cutaneous Merkel-Cell Carcinoma

Paul M. Busse, M.D., Ph.D., John R. Clark, M.D., Victorine V. Muse, M.D., and Vincent Liu, M.D.

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Presentation of Case

Dr. Gregory K. Robbins (Infectious Diseases): A 63-year-oldman was referred to the clinic for head and neck cancer, a multidisciplinaryunit of this hospital, for management of cutaneous Merkel-cellcarcinoma. He had been well until 3 months earlier, when henoted a small, painless nodule on the superior, right-centralaspect of his forehead. During the next 3 weeks, this nodulegrew slowly, and a second, pea-size, painless nodule developedin front of his right ear. Pathological examination of a biopsyspecimen of the lesion on the forehead indicated a small-cellcarcinoma that was thought to be consistent with Merkel-cell. . . [Full Text of this Article]

Pathological Discussion

Discussion of Management

Decision Making for Stage II Merkel-Cell Carcinoma

Anatomical Diagnosis

Source Information

From the Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School (P.M.B.); the Department of Hematology–Oncology, Massachusetts General Hospital, and the Department of Medicine, Harvard Medical School (J.R.C.); the Department of Radiology, Massachusetts General Hospital and Harvard Medical School (V.V.M.); and the Departments of Dermatology and Pathology, University of Iowa Carver College of Medicine, Iowa City (V.L.).