Presentation of Case Dr. Michael Sherling (Dermatology): A 44-year-old woman was admitted to this hospital because of generalized, painful, ulcerated cutaneous lesions. The patient had been well, except for eczema, until 4 years before admission, when erosions on the scalp developed, followed by a generalized…

…after prolonged fasting is rare. We recorded anthropometric, biochemical, and endocrine changes during the refeeding period after a much-publicized 44-day fast by David Blaine, a performance artist; we compared the findings with results obtained from a control group of 16 age-matched men who had a similar…

Presentation of Case A 44-year-old man was seen in the clinic because of a right atrial mass. Six years earlier, the patient had been found to have Pneumocystis carinii pneumonia and human immunodeficiency virus (HIV) infection. He had returned to a satisfactory state of health with the use of highly…

Presentation of Case A 44-year-old woman was admitted to this hospital because of abdominal pain, chills, fever, and jaundice. The patient, a native of southern China, had been treated for intrahepatic stones by lithotripsy five years before admission to this hospital. Two years after the procedure…

…was available, such therapy was started before admission in 30 patients (15%), on admission in 117 patients (59%), within 48 hours after admission in 44 patients (22%), and more than 48 hours after admission in 7 patients (4%). Patients received a median of two antibiotics (range, one to seven); 70% of…

There's nobody better than the Brits at breaking scientific bad news in plain, blunt language. Consider this dispiriting assessment of medical and public health professionals' track record to date on helping overweight children: “Regrettably, most dietary (and physical activity) prescriptions for…

This book covers many of the topics in vascular medicine that currently are prominent in the scientific, clinical, and lay press. Part I deals with mechanisms of hypercoagulability; the roles of cells, cytokines, and inflammation in the pathogenesis of arterial disease; genetic and environmental…

The abuse of psychoactive substances is among the leading causes of disability and criminal activity in the world. Drug addiction is difficult to study. Most drug transactions are effected illegally, which limits the acquisition of accurate data on drug abuse. However, in 1997, the United Nations…

…square meter of body-surface area, administered by intramuscular injection. A higher dose (60 mg per square meter) does not increase the success rate. 44 Oral administration (25 or 50 mg) is also effective. 47 48 49 Three to seven days after the methotrexate has been administered, misoprostol (800 μg…

…not symptoms of lead poisoning. However, the CDC made no specific recommendation about chelation therapy in children with blood lead levels of 20 to 44 μg per deciliter (1.0 to 2.1 μmol per liter). 9 Because of the increase in screening, the wide availability of an oral chelator, and the lack of data…

…history of peripartum cardiomyopathy who had had a subsequent pregnancy. We were able to review the clinical and echocardiographic information for 44 of these women, of whom 23 were white, 16 were black, and 5 were Hispanic. Their ages at the time of diagnosis of peripartum cardiomyopathy ranged from…

…(14%). Primary Outcome In the cooled group, 42 infants died and 32 survived with severe neurodevelopmental disability, whereas in the noncooled group, 44 infants died and 42 had severe disability ( Table 2) (relative risk for either outcome, 0.86; 95% confidence interval [CI], 0.68 to 1.07; P=0.17). The…

…replicates in regional lymph nodes and is disseminated through the lymphatic system and blood to other tissues. 44 Replication in the reticuloendothelial system and skin results in viremia. 44 The incubation period ranges from 3 to 14 days, but it is usually 4 to 7 days. Infection with dengue virus of…

…from 147 patients in the dexamethasone group who had disease progression and subsequently crossed over to receive bortezomib in a companion study (44 percent). The time to a first skeletal event and the rate of grade 3 or higher infections did not differ significantly between the two treatment groups…

…Table 1]) and at least one of two laboratory criteria. None of the other protean clinical manifestations of the antiphospholipid syndrome, 2 41 42 43 44 45 46 such as thrombocytopenia, are included in the clinical criteria. Although such features have been associated with antiphospholipid antibodies,…

…methods were used for HPV types 16, 18, 31, 33, 35, 39, 45, 51, 52, 54, and 56. A second round was performed for HPV types 6, 11, 26, 34, 40, 42, 43, 44, 53, 58, 59, and 68. A third round was performed for HPV types 57, 61, 66, 70, 72, 73, 81 (CP8304), 82 (W13B/MM4 subtype and IS39 subtype), 83, and CP6108…

…center treated 15 patients, another center 4 patients, 3 centers treated 2 patients each, and the remaining centers treated a single patient each). All 44 patients were treated, and 43 completed therapy according to the protocol; the remaining patient stopped therapy after 12 weeks because of hair loss…

…Women 21 to 44 years old made up 75.4 percent of all women who purchased handguns. Among these younger women, more than half of those who died during the first year (51.9 percent) had committed suicide, and 37.0 percent had committed suicide with use of a firearm. Among all women 21 to 44 years old in…

…Intravenous Thrombolytic Therapy The results of four phase 3 trials of intravenous t-PA for the urgent treatment of patients with stroke have been reported. 44 45 46 47 The FDA approved this treatment on the basis of the results of the National Institute of Neurological Disorders and Stroke Recombinant Tissue…

…of gases drawn while the patient was breathing 6 liters of oxygen by nasal cannula, revealed a pH of 7.41, a partial pressure of carbon dioxide of 44 mm Hg (reference range, 35 to 50), and a partial pressure of oxygen of 205 mm Hg (reference range, 40 to 90, while breathing ambient air). The chest…