
In this phase 2, randomized, placebo-controlled trial of 111 patients who had Behçet’s syndrome with oral ulcers, apremilast, an oral phosphodiesterase-4 inhibitor that modulates several inflammatory pathways, reduced the number of ulcers and pain from ulcers at 12 weeks.

Routine preoperative testing is not recommended before cataract surgery. In this analysis of Medicare claims data, preoperative testing was common and varied widely among ophthalmologists; the ophthalmologist performing the surgery was the strongest predictor of testing.
Ask the authors about this study in the NEJM Group Open Forum on Medstro.com (free registration required).

(DOI: 10.1056/NEJMsa1414929)
In 2012, a total of 32 provider organizations entered the Medicare Pioneer accountable care organization program, which gives financial incentives for reduced spending. A comparison of spending for ACO patients and controls suggests there were modest savings in year 1.
(DOI: 10.1056/NEJMp1501362)
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(DOI: 10.1056/NEJMp1501362)
(DOI: 10.1056/NEJMsa1414929)
(DOI: 10.1056/NEJMoa1404881)
(DOI: 10.1056/NEJMoa1414216)













