Ebola in DRC
original article Online First

In the midst of the West Africa epidemic, Ebola virus disease was identified in the equatorial country of the Democratic Republic of Congo. Epidemiologic and molecular data show that the DRC outbreak is related to previous EVD outbreaks there and did not spread from West Africa. A video shows field workers in DRC.

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Goal-Directed Resuscitation in Septic Shock
Original Article
Published Online: October 1, 2014

For more than a decade, early treatment of sepsis has been driven by algorithms. In this study conducted predominantly in Australia and New Zealand, the use of algorithm-based treatment was not superior to usual care.

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A Chilly Fever
interactive medical case

This interactive feature presents the case of a 30-year-old man with a 1-week history of fevers associated with shaking chills, nausea, and severe headaches. He had previously been well.

Test your diagnostic and therapeutic skills and compare your performance with that of others.

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Chimeric Antigen Receptor T Cells for Leukemia
ORIGINAL ARTICLE

In this study, adoptively transferred T cells transfected with anti-CD19 and activating signal–generating molecules led to complete remission in 90% of patients with relapsed and refractory acute leukemia, and overall survival at 6 months was 78%.

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Innovation in Health Care Leadership
Perspective Roundtable
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Ebola Outbreak

Ebola Outbreak

Clinical reports, commentary, and other resources on the Ebola outbreak.

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Current Issue: October 16, 2014

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Published Online: September 23, 2014
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images in clinical medicine
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case records of the massachusetts general hospital
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clinical implications of basic research

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