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Thumbnail Graphic -- Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer
Original Article

The authors report increased survival among patients with advanced hormone-refractory prostate cancer who were vaccinated against a tumor antigen. Administering three doses of sipuleucel-T immunotherapy over a 1-month period improved overall survival by 4 months.

Editorial
Original Article
  • CME

In this clinical trial of dispatcher-assisted bystander cardiopulmonary resuscitation (CPR), results were similar with chest compressions alone and with chest compressions plus rescue breathing. However, patients with a cardiac cause of the arrest and those with shockable rhythms fared better with chest-compression-only CPR.

Editorial
Thumbnail Graphic -- The Renaissance in HIV Vaccine Development
Perspective
  • Free Full Text

From July 18 through July 23, delegates from around the globe convened for the biennial International AIDS Conference in Vienna. The authors describe a series of recent advances that collectively represent a renaissance in HIV vaccine development.

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Current Issue: July 29, 2010

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Original Article
  • CME
Original Article
Clinical Therapeutics
  • CME
Images in Clinical Medicine
Images in Clinical Medicine
Case Records of the Massachusetts General Hospital
  • CME
Editorial
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Editorial
Clinical Implications of Basic Research

Perspective

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Geographic Variation in Medicare Drug Spending
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The Renaissance in HIV Vaccine Development -- Future Directions
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Image Challenge

Thumbnail Graphic -- Image Challenge

What is the diagnosis?

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Thumbnail Graphic -- Pneumothorax after a Common Procedure

A 92-year-old patient was admitted with severe ischemic stroke causing altered mental status. After insertion of a small-caliber nasogastric tube for feeding, the patient had shortness of breath.

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