This study shows that for variants initially classified as pathogenic that were later reclassified as benign, the misclassification would have been prevented had racially diverse populations been considered in the original studies of the variants.
When it comes to melanoma, age matters — specifically, the molecular changes in the vicinity of the melanoma cell in the skin of older persons.
In six children, biotin produced changes in thyroid-function tests that mimic those seen in Graves’ disease.
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Herpes simplex virus type 1 and type 2 cause genital herpes. Antiviral therapy is used for symptomatic outbreaks, and as daily suppressive therapy, it reduces recurrences of symptoms, asymptomatic viral shedding, and the risk of HSV-2 transmission.
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Legislation regarding mental health parity and other health policy reforms have improved access to treatment for mental health and substance-use disorders, but ongoing problems include a shortage of mental health specialists and lack of systemwide integration.
(DOI: 10.1056/NEJMp1609905)
(DOI: 10.1056/NEJMp1607850)
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(DOI: 10.1056/NEJMp1609905)
(DOI: 10.1056/NEJMc1607262)
(DOI: 10.1056/NEJMp1607850)
(DOI: 10.1056/NEJMp1607958)
(DOI: 10.1056/NEJMp1608289)
